Innocore is a specialist drug delivery company focused on the development of long-acting injectable (LAI) formulations for peptides, biologics, oligonucleotides, and selected small molecules. We combine proprietary biodegradable polymer technologies, deep formulation expertise, and integrated development capabilities to create sustained-release injectable drug products with customized pharmacokinetic profiles.
Our technologies are broadly applicable across therapeutic areas such as site specific and or chronic disease. We currently see particularly strong interest in endocrinology (e.g. obese, diabetic, hormone), cardiometabolic disease, immunology, inflammation, ophthalmology, neurology, oncology, infectious diseases, and veterinary medicine.
Innocore combines over 20 years of experience in biodegradable polymer science with proprietary SynBiosys® polymer technology platforms specifically designed to address the challenges associated with peptides and biologics. Our technologies enable tunable release kinetics while preserving API integrity and allowing scalable manufacturing.
Innocore is headquartered in Groningen, The Netherlands, where we operate state-of-the-art laboratories for polymer synthesis, formulation development, analytical characterization, and process development.
SynBiosys® is Innocore’s proprietary biodegradable polymer platform for long-acting injectable drug delivery. The platform enables the development of highly customizable sustained-release formulations with release durations ranging from weeks to months and supports multiple dosage forms, including microspheres, implants, and in situ forming depots.
SynBiosys® has been designed specifically for challenging APIs, including:
Compared with traditional PLGA-based systems, SynBiosys® can offer:
Yes. SynBiosys® polymers have demonstrated safety and efficacy in multiple preclinical and clinical programs, and products incorporating SynBiosys® technology have reached regulatory approval.
Our technology platforms support several long-acting dosage forms, including:
Depending on the API, indication, and administration route, sustained release periods ranging from several weeks up to 12 months can be achieved.
Our platforms support various administration routes, including:
Peptides and biologics are often sensitive to heat, organic solvents, pH changes, enzymatic degradation, aggregation, and chemical modification. Developing stable long-acting formulations therefore requires specialized polymer systems, analytical methods, and formulation expertise.
Yes. Biologics and peptides represent a strategic focus area for Innocore. Our technologies have been specifically engineered to preserve biological activity and structural integrity during formulation, storage, and sustained release.
Examples include:
We provide integrated development support, including:
Yes. We frequently engage with clients at the discovery and preclinical stages to identify the optimal long-acting formulation strategy before significant development investments are made.
We support clients through process development, scale-up, technology transfer, and manufacturing strategy. For GMP manufacturing, we collaborate with a network of specialized manufacturing partners.
Our partners include:
We offer flexible collaboration structures, including:
Absolutely. We regularly execute confidential feasibility and evaluation studies under appropriate confidentiality agreements.
Intellectual property arrangements are tailored to each collaboration. Depending on the project structure, outcomes may include customer-owned IP, jointly developed IP, or licensing arrangements involving Innocore’s proprietary technology platforms.
Yes. Innocore owns extensive intellectual property covering its SynBiosys® polymer platforms, formulations, manufacturing processes, and applications.
The best way is to contact our business development team. Following a confidential discussion, we can typically provide an initial assessment of the feasibility, opportunities, and potential challenges for developing a long-acting injectable formulation.
Please contact us through the contact form on our website or reach out directly to our team to discuss your program and objectives.